Exercise can reverse dementia

CSL Florey Medal recipient, Professor Perry Bartlett
Credit: Shannons

At least in mice – but CSL Florey Medal recipient, Professor Perry Bartlett, says his team are gearing up to start human experiments next year.

“Too short or too long interestingly, & nothing happens, so there’s a sweet spot of exercise that's able to activate the new neurons & also result in this cognitive improvement.”

http://www.abc.net.au/news/2015-11-11/brain-researcher-perry-bartlett-awarded-florey-medal/6932586

https://www.uq.edu.au/news/article/2015/11/top-brain-researcher-awarded-csl-florey-medal

http://www.scienceinpublic.com.au/floreymedal/2015cslrelease

http://discovery.wehi.edu.au/timeline/neuro-immunology-lab / world’s first neuro-immunology laboratory institute headed by Perry Bartlett Professor Perry Bartlett colleagues discover existence stem cells brain produce new neurons new hope patients brain injuries degenerative conditions Alzheimer’s disease Perry Bartlett immunologist neurologist Perry Bartlett medical research PhD immunology work Walter and Eliza Hall Institute Jacques Miller Gus Nossal Sir Macfarlane Burnet immunology neuroscience finishing PhD Johns Hopkins University USA cell biology MHC major histocompatibility complex molecules immune system University College London Professor Martin Raff immunology neurobiology identifying different types brain cells first monoclonal antibodies identified subsets nerve cells brain neuroscience immunological new field of research Gus Nossal Hall Institute world’s first neuro-immunology laboratory Walter and Eliza Hall Institute major discoveries MHC molecules brain immune-response free zone molecules inflammatory processes basic neuroscience understand different types of cells development brain investigating stem cells give rise neurones patients with brain injuries stem cells developmentally adult brain cells able to make new neurones brains having capacity make new nerve cells lose cells with age gain 10 years investigation adult brain did have the capacity to produce new neurons nerve cells hope brain injuries degenerative conditions dementia Alzheimer’s disease scepticism furore capacity meaningful role in the brain remnant development new nerve cells important redefining brain isolated characterised brain stem cells brain capacity make new nerve cells important normal function source regeneration reverse decline of cognition animals further research in humans reverse cognitive decline old mice activating production new nerve cells sweet spot exercise exercise enough but not too much change in the brain’s biochemistry new Queensland Brain Institute University of Queensland heavy-hitting medical research biotechnology sector neuroscience institute thinking techniques commitment long-haul investigation stem cells lineages regulation stem cells neuroscience Metcalf haemopoietic blood system science driven ideas neuroscientists how lineages worked stem cells were important reductionist approach fundamental processes regulate production nerve cells start developmentally adult painstaking narrative /