Why am I still fat?

Sustained weight loss is a difficult & complex question, apects of which are addressed in the video below. The most interesting part triggers my, “If it’s too good to be true, it probably is,” reflex, but the experimental evidence is in: rats fed a diet equivalent to thickshakes, burgers & fries unsurprisingly, gain weight & develop other symptoms of obesity, such as inflammation, increased blood pressure, insulin insensitivity & reduced heart & liver function. When plant juice, rich in the purple anti-oxidant pigment anthocyanin was added to the diet, all of the harmful effects were reversed!

Starts at 16:50 mark.



Transcript of the video
http://www.abc.net.au/catalyst/stories/4327346.htm

More about anthocyanin & the Queen Garnet Plum
http://www.abc.net.au/news/2015-02-14/antioxidant-rich-plum-to-fight-obesity/6094914 / Associate Professor Amanda Salis University of Sydney clinical weight loss trials finding better ways to lose weight keep it off for long term shape of the human body changing dramatically prevalence of obesity has doubled in the last few decades Professor Stephen Simpson proportion of the population that was considered obese epidemic number of obese children has tripled population is getting fatter nine million adults are overweight explosion of fat-related diseases two out of three Australians overweight obesity is the new normal BMI bodyweight science fight against fat intervene kids at risk before they're born conventional genetics at play Dr Nathan O'Callaghan 50 genetic variants associated with obesity contributes 5% of the variation in body size increase in global obesity can't just be explained by eating too much exercising too little our bodies in our brains environment Why am I still fat? your efforts to lose weight helping you to keep the kilos on in-built survival mechanism controlled by our brain the famine reaction effects famine reaction makes you hungrier increases your drive to eat famine reaction famine reaction broken my diet I gained weight dieted myself fat personal experience motivates her research TEMPO diet trial University of Sydney world-first research three-year study long-term effects weight loss in 100 post-menopausal women compared effects fast versus slow weight loss famine reaction head-to-head two types of diets are being compared very low energy diet of 800 calories a day fast weight loss conventional diet slow weight loss women study keen gardener medical researcher participants controlling weight classic yo-yo dieter yoyo dieting yo-yo dieting eating well cooking slow and steady diet TEMPO trial dieter heart attack lean leaner weighed more diet fast-track diet rapid weight loss diet trial obese don't notice putting weight on like an addiction dieters who lose bodyweight put it back on again within five years why is maintaining weight loss so difficult why do so many dieters hit a wall the longer you carry weight the harder it is to lose it hypothalamus in your brain resets the amount of fat your body defends famine reaction keeps you craving food lose weight feel hungry DEXA scan type of X-ray measures the mass of fat muscle lean tissues mineral density of bone calculate how much fat in the different regions of the body impact of the famine reaction measure body composition famine reaction alters your hormones make your body inclined to hold onto fat midriff region makes your body more inclined lose lean tissues muscle and bone fat mass lean mass calorimetry hood measures metabolic rate how much fat burning famine reaction increases drive to eat makes body more fuel-efficient more fuel efficient relaxed awake measuring resting energy expenditure changes with weight loss affects how many kilojoules you burn over the course of the day affects how much you can eat without putting on weight TEMPO trial testing participants reporting how hungry they feel rapid weight loss should be avoided makes the famine reaction stronger first progress results diets don't work for everybody more drastic intervention to lose weight rapidly making it harder for food to fit in your stomach lap-band operation unfit feel unhealthy never feel well go out for walks food obsessed with food think about food all the time lap-band surgery inability to lose weight type 1 diabetes high blood pressure high BMI lose 30kg bariatric surgeon life-threatening diseases come with obesity lap-band tool lap-band under your skin stomach adjustable keyhole surgery relatively safe nerves that control appetite neurologist Amanda Page nerves allow the stomach communicate with the brain difficult situation once you're obese to actually lose that weight again weight gain resets the sense of feeling full stomach mouse nerves fire when receptors respond to stretching tension-sensitive nerve in the stomach nerve record the nerve activity nerve activity increases signals to the brain full regulating appetite brain wouldn't know when to stop eating compares stomachs of lean mice obese mice response to stretch dramatically humans obese person just stop eating reset the receptors lean condition non-surgical therapy for obesity Bariatric surgeon Stephen Wilkinson install lap-band laparoscopic instruments lap-band abdomen stomach band oesophagus stomach simple operation lose excess weight our society values thinness and health encourages us to overeat and consume more blame obesity on food manufacturers resistance from the industry labelling healthy choice nutritional individual nutrient groups finding best mix in a balanced diet carbohydrate protein fats appetite control automatically priority protein fats carbohydrates taste like protein lipsmacking amino acid umami flavours diluting protein makes food cheaper to make good for business bad for appetite control savoury snack food industry potato chip protein decoy tastes like protein bodies evolved associate flavour cues with protein loaded up fat carbs carbohydrates protein appetite unfulfilled continue snack eat more subversive extra calories why we get fat white fat cells protect us providing a safe home for lipids keep the fats out of our organs overloaded swell and burst leaking lipid into the bloodstream body's defences red alert inflammatory reaction chronic low-grade inflammation causes organ damage cardiovascular fatty liver disease insulin resistance diabetes Professor Lindsay Brown stops obesity stops inflammation Toowoomba University of Southern Queensland medicinal power natural foods counteract obesity reverse inflammatory effects fruit and vegetables color colour color colour purple anthocyanin natural pigment range of compounds in plants keep systems healthy ours too veggie vegetable highest anthocyanin purple carrots are by far the best amazing amount of anthocyanin fruits queen garnet plum ordinary purple plum five or ten times as much of the purple colour in it anthocyanins rats fattened diet similar to thickshakes burgers fries BMI Body Mass Index BMI most of the Australian human population obesity obese rats bodies blood pressure going up quite dramatically heart function is going down liver function going down abdominal fat pad increased hormones go up whole of the body affected characteristic of obesity Professor Lindsay Brown inflammatory response every organ organ immune anthocyanin-rich anthocyanin rich juice food half the rats anthocyanins purple carrots queen garnet plums completely changes changed the diet high-carbohydrate high-fat diet intervention all of those parameters characterise obesity back to normal billion-dollar billion dollar multinational company-type company type product carrot plum rats human clinical trials food driving obesity young children nearly one in four children are overweight or obese obesity leading threat to public health new science emerging research synthetic chemicals act like hormones change the way our bodies react to fat obesogens oestrogen estrogen oestrogen estrogen mimic exposed to these chemicals phthalates bisphenols phthalates bisphenols in their bodies plasticisers plasticisers bisphenols BPA BPA almost impossible common in our food packaging and consumer goods Dr Bridget Maher used as a resin lining of household water supply our drinking water is often contaminated with BPA chemicals exposure in children affect obesity risk rest of their lives measure their chemical load sample short-lived chemicals collect samples urine breast milk house dust child's body study levels of chemical exposure growth rates birth body composition measured babies baby's per cent body fat lean body mass first study short-lived environmental chemicals obesity first six months of life growth rates BMI slow weight gain through diet increase risk of obesity metabolic disease later in life BPA endocrine disrupter interferes with the hormone system could obesogens reshaping our genetic destiny science epigenetics environment changes structure gene function of the gene epigenetics normal human development environmental toxicants things go wrong losing weight slow and steady diet fast-track diet fat lose low-energy diet famine reaction making her want to eat more fast weight loss famine reaction appetite eating crash diets which diet is best study clinical trial participants famine reaction hunger famine reaction lap-band operation weight changed lap-band lap-band medical reasons obesity weight healthy healthy diet more exercise better for everyone losing weight why am I still fat Why am I NOT fat new science improve public health efforts tackle obesity getting fat being lazy lacking willpower the full picture powerful biological and environmental reasons why we put weight on regain manage to lose health /